Drug resistance, Massive increase in antimicrobials use in animals to lead to widespread drug resistance in humans
The researchers, from ETH Zürich, Princeton, and the University of Cambridge, conducted the first global assessment of different intervention policies that could help limit the projected increase of antimicrobial use in food production. Their results, reported in the journal Science, represent an alarming revision from already pessimistic estimatesmade in 2010, pushed up mostly by recent reports of high antimicrobial use in animals in China.
In modern animal farming, large quantities of antimicrobials are used for disease prevention and for growth promotion. “Worldwide, animals receive almost triple the amount of antibiotics that people do, although much of this use is not medically necessary, and many new strains of antibiotic-resistant infections are now common in people after originating in our livestock,” said co-author Emma Glennon, a Gates Scholar and PhD student at Cambridge’s Department of Veterinary Medicine. “As global demand for meat grows and agriculture continues to transition from extensive farming and smallholdings to more intensive practices, the use of antimicrobials in food production will increasingly threaten the efficacy of these life-saving drugs.”
Global policies based on a user fee and stricter regulation could help mitigate those ominous projections. “Under a user fee policy, the billions of dollars raised in revenues could be invested in the development of new antimicrobial compounds, or put towards improving farm hygiene around the world to reduce the need for antibiotics, in particular in low- and middle-income countries,” said Dr. Thomas Van Boeckel from ETH Zurich, the study’s first author.
Cambridge says that compared to a business as usual scenario, a global regulation putting a cap of 50 mg of antimicrobials per kilogram of animal per year in OECD countries could reduce global consumption by 60 percent without affecting livestock-related economic development in low-income countries.
However, such a policy may be challenging to enforce in resource-limited settings. An alternative solution could be to impose a user fee of 50 percent of the current price on veterinary antimicrobials: this could reduce global consumption by 31 percent and generate yearly revenues of between $1.7 and 4.6 billion.
An important limiting factor in performing this global assessment was accessing sufficient data on veterinary antimicrobial sales volumes and prices. The present study is based on publicly available data, limited to thirty-seven countries. Representatives from the animal health industry were approach for this study but all declined to share information on antimicrobial sales or prices.
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The amount of antimicrobials given to
animals destined for human consumption is expected to rise by a
staggering 52 percent and reach 200,000 tons by 2030 unless policies are
implemented to limit their use, according to new research. represent an
alarming revision from already pessimistic estimates made in 2010,
pushed up mostly by recent reports of high antimicrobial use in animals
in China.
The amount of antimicrobials given to animals destined for
human consumption is expected to rise by a staggering 52 percent and
reach 200,000 tons by 2030 unless policies are implemented to limit
their use, according to new research.The researchers, from ETH Zürich, Princeton, and the University of Cambridge, conducted the first global assessment of different intervention policies that could help limit the projected increase of antimicrobial use in food production. Their results, reported in the journal Science, represent an alarming revision from already pessimistic estimatesmade in 2010, pushed up mostly by recent reports of high antimicrobial use in animals in China.
In modern animal farming, large quantities of antimicrobials are used for disease prevention and for growth promotion. “Worldwide, animals receive almost triple the amount of antibiotics that people do, although much of this use is not medically necessary, and many new strains of antibiotic-resistant infections are now common in people after originating in our livestock,” said co-author Emma Glennon, a Gates Scholar and PhD student at Cambridge’s Department of Veterinary Medicine. “As global demand for meat grows and agriculture continues to transition from extensive farming and smallholdings to more intensive practices, the use of antimicrobials in food production will increasingly threaten the efficacy of these life-saving drugs.”
Global policies based on a user fee and stricter regulation could help mitigate those ominous projections. “Under a user fee policy, the billions of dollars raised in revenues could be invested in the development of new antimicrobial compounds, or put towards improving farm hygiene around the world to reduce the need for antibiotics, in particular in low- and middle-income countries,” said Dr. Thomas Van Boeckel from ETH Zurich, the study’s first author.
Cambridge says that compared to a business as usual scenario, a global regulation putting a cap of 50 mg of antimicrobials per kilogram of animal per year in OECD countries could reduce global consumption by 60 percent without affecting livestock-related economic development in low-income countries.
However, such a policy may be challenging to enforce in resource-limited settings. An alternative solution could be to impose a user fee of 50 percent of the current price on veterinary antimicrobials: this could reduce global consumption by 31 percent and generate yearly revenues of between $1.7 and 4.6 billion.
An important limiting factor in performing this global assessment was accessing sufficient data on veterinary antimicrobial sales volumes and prices. The present study is based on publicly available data, limited to thirty-seven countries. Representatives from the animal health industry were approach for this study but all declined to share information on antimicrobial sales or prices.
Source